Turning Cancer Cells Against Themselves

Cancer Cell Illustration

Image credit: Adobe Stock

Company Overview

Founded: June 2018
Location: Redwood City, CA
Mission: Make cancer a benign experience

Technology

Programmable genetic constructs
Activate only in cancer cells
Force cancer cells to self-reveal and self-destruct

Key People

Cyriac Roeding

Cyriac Roeding
Co-founder & CEO

Dr. Sam Gambhir

Dr. Sam Gambhir
Co-founder

David Suhy

David Suhy
Chief Scientific Officer

Funding & Recognition

  • $40 million Series A led by Khosla Ventures
  • Investors include Andreessen Horowitz, Perceptive Advisors, Casdin Capital, Sands Capital, Marc Benioff
  • World Economic Forum Global Innovator
  • Fast Company's 2021 World Changing Ideas

Innovative Approach

  1. Inject bioengineered DNA into the body
  2. DNA enters cancer cells, forcing production of synthetic biomarkers
  3. Detect biomarkers through breath or blood tests
  4. Use radioactive tracer to make tumors visible in scans

Applications & Status

Applications: Diagnostic monitoring, pre-treatment scans, surgical guidance, post-treatment monitoring

Status: Successful trials in mice and dogs; human trials began in 2021